Hypogonadotropic Hypogonadism Revisited

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Hypogonadotropic Hypogonadism Revisited

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I-3: Hypogonadotropic Hypogonadism

Hypogonadotropic hypogonadism (HH) is an uncommon cause of male infertility and a congenital or secondary disorder characterized by delayed or absent sexual maturation. Congenital abnormalities leading to HH are usually the consequence of deficient GnRH secretion occurring either in isolation (idiopathic hypogonadotropic hypogonadism (IHH)), or in association with anosmia (Kallmann syndrome; KS...

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Reversal of idiopathic hypogonadotropic hypogonadism.

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An isolated deficiency of pituitary gonadotropins was demonstrated in six 46 XY males, 22 to 36 years of age, with and without anosmia. Undetectable or low levels of serum follicle-stimulating hormone (FSH) and luteinizing hormone (LH) clearly separated hypogonadotropic from normal adult males. Chronic (8-12 wk) administration of clomiphene citrate caused no increase in serum FSH or LH in gonad...

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ژورنال

عنوان ژورنال: Clinics

سال: 2013

ISSN: 1807-5932

DOI: 10.6061/clinics/2013(sup01)09